Difficulties and possible solutions in the genetic management of mtDNA disease in the preimplantation embryo.
Families who have had a child die of a severe, maternally inherited mitochondrial DNA (mtDNA) disease are usually desperate to avoid having further affected children. Here we discuss the problems of applying classical genetic management to mtDNA diseases (Poulton and Turnbull, 2000) and the biology...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2007
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