The involvement of hypoxia in APOBEC-mediated mutagenesis in multiple cancers

<p>Mutational signatures have been studied to associate mutations to their originating causes. One such signature is that of the APOBEC family of proteins. APOBEC proteins are normally involved in innate immunity, playing a role in the defence against foreign genetic material by inducing mutat...

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Bibliographic Details
Main Author: Liang, J
Other Authors: Buffa, F
Format: Thesis
Language:English
Published: 2018
Subjects: