The involvement of hypoxia in APOBEC-mediated mutagenesis in multiple cancers

<p>Mutational signatures have been studied to associate mutations to their originating causes. One such signature is that of the APOBEC family of proteins. APOBEC proteins are normally involved in innate immunity, playing a role in the defence against foreign genetic material by inducing mutat...

Ausführliche Beschreibung

Bibliographische Detailangaben
1. Verfasser: Liang, J
Weitere Verfasser: Buffa, F
Format: Abschlussarbeit
Sprache:English
Veröffentlicht: 2018
Schlagworte: