Induction of dominant transplantation tolerance by an altered peptide ligand of the male antigen Dby.
T cell reactivity to minor histocompatibility (mH) antigens is responsible for rejection of HLA-matched allografts, limiting the effectiveness of transplantation for the treatment of end-stage organ failure. The deadbox gene Dby is located on the Y chromosome and encodes an mH antigen that prompts r...
| Main Authors: | , , |
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| Format: | Journal article |
| Jezik: | English |
| Izdano: |
2004
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