A human Phase I/IIa malaria challenge trial of a polyprotein malaria vaccine.

A human Phase I/IIa malaria challenge trial of a polyprotein malaria vaccine.

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We examined the safety, immunogenicity and efficacy of a prime-boost vaccination regime involving two poxvirus malaria subunit vaccines, FP9-PP and MVA-PP, expressing the same polyprotein consisting of six pre-erythrocytic antigens from Plasmodium falciparum. Following safety assessment of single do...

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Bibliographic Details
Main Authors: Porter, D, Thompson, F, Berthoud, T, Hutchings, C, Andrews, L, Biswas, S, Poulton, I, Prieur, E, Correa, S, Rowland, R, Lang, T, Williams, J, Gilbert, S, Sinden, R, Todryk, S, Hill, A
Format: Journal article
Language:English
Published: 2011

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