The use of HLA class I tetramers to design a vaccination strategy for melanoma patients.

Progress in human tumor immunology has recently been accelerated by new assays for antigen-specific cytotoxic T lymphocytes (CTLs). We have used tetrameric MHC class I complexes (tetramers) to study melanoma-specific CTLs both in vivo and in vitro, and have utilized the results to optimize vaccinati...

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Bibliographic Details
Main Authors: Palmowski, M, Salio, M, Dunbar, R, Cerundolo, V
Format: Journal article
Language:English
Published: 2002