The use of HLA class I tetramers to design a vaccination strategy for melanoma patients.
Progress in human tumor immunology has recently been accelerated by new assays for antigen-specific cytotoxic T lymphocytes (CTLs). We have used tetrameric MHC class I complexes (tetramers) to study melanoma-specific CTLs both in vivo and in vitro, and have utilized the results to optimize vaccinati...
| Glavni autori: | , , , |
|---|---|
| Format: | Journal article |
| Jezik: | English |
| Izdano: |
2002
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