Shape-morphing of an artificial protein cage with unusual geometry induced by a single amino acid change

Artificial protein cages are constructed from multiple protein subunits. The interaction between the subunits, notably the angle formed between them, controls the geometry of the resulting cage. Here, using the artificial protein cage, “TRAP-cage”, we show that a simple alteration in the position of...

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Bibliographic Details
Main Authors: Sharma, M, Biela, AP, Kowalczyk, A, Borzęcka-Solarz, K, Piette, BMAG, Gaweł, S, Bishop, J, Kukura, P, Benesch, JLP, Imamura, M, Scheuring, S, Heddle, JG
Format: Journal article
Language:English
Published: American Chemical Society 2022