The regulation and inhibition of P-TEFb

The regulation and inhibition of P-TEFb

<p>Correct regulation of transcription is essential for maintaining a healthy cellular state. During transcription RNA polymerase II (Pol II) proceeds in a regulated manner through several transitions to ensure appropriate control of synthesis and enable correct processing of the pre-RNA. Shor...

Deskribapen osoa

Xehetasun bibliografikoak
Egile nagusia:	Hole, A
Beste egile batzuk:	Noble, M
Formatua:	Thesis
Hizkuntza:	English
Argitaratua:	2011
Gaiak:	Molecular biophysics (biochemistry) Biochemistry

Antzeko izenburuak

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Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by non-interacting residues
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Biophysical and magnetic resonance studies of membrane proteins
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Structural studies of a membrane embedded chloride channel from E.Coli, a prokaryotic homologue of ClC channels
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Argitaratua: (2001)

Interactions of Neisseria meningitidis with the human immune system
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Biophysical studies of membrane protein structure and function
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Radiation damage in protein crystals examined under various conditions by different methods
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Determination of X-ray flux using silicon pin diodes
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Fluorescence studies of influenza RNA and RNA polymerase
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Structural studies on determinants of receptor/ligand binding in the tumour necrosis factor and T cell receptor protein families
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Structural studies of malaria proteins
nork: Mayer, C
Argitaratua: (2012)

Structural studies on determinants of receptor/ligand binding in the tumour necrosis factor and T cell receptor protein families
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Argitaratua: (2005)

Structural studies of cell adhesion and division
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Temporary serine protease inhibition and the role of SPINK2 in human bone marrow
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The relationship between flagellar motor dynamics and the proton motive force
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A biophysical study of the G protein coupled receptor neurotensin receptor 1
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Control of the unidirectional motor in Rhodobacter sphaeroides
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Argitaratua: (2009)

Structural characterisation of the interaction between Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) and their human ligands in severe malaria
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Argitaratua: (2012)

Structural, biochemical and computational studies of TRP channel transmembrane domain modularity
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Structure-function studies of the bacterial dsDNA translocase FtsK
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Argitaratua: (2010)

Molecular and structural characterisation of the human Fibrillin-1 N-C terminal interaction
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Argitaratua: (2013)

Ion channels: structure of a molecular brake
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Argitaratua: (1999)

The dielectric properties of water within model transbilayer pores
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Argitaratua: (1997)

The molecular basis for ER tubule formation
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Argitaratua: (2015)

Substrate recognition by the proteasome
nork: Boehringer, J
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K+ channels: gating mechanisms and lipid interactions
nork: Schmidt, M
Argitaratua: (2013)

Computational studies of signalling at the cell membrane
nork: Lumb, CN
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Studying marcomolecular transitions by NMR and computer simulations
nork: Stelzl, LS
Argitaratua: (2014)

Structure and dynamics of picornavirus capsids to inform vaccine design
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Argitaratua: (2014)

Mutational analysis of isoform selectivity and conformational equilibria in protein kinase inhibition
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Mechanisms of transcription regulation by full-length CREB
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Mass Photometry of Membrane Proteins
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The influence of environment: simulations of the influenza BM2 proton channel
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Argitaratua: (2012)

Improving rapid affinity calculations for drug-protein interactions
nork: Ross, G
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Structural studies of cell surface signalling molecules for neuronal guidance and connectivity
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Molecular characterisation of bacterial proteins that interact with sulfur or nitrogen compounds
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Kinetics and mechanics of two-dimensional interactions between T cell receptors and different activating ligands.
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Single-molecule imaging of electroporated chemotaxis proteins in live bacteria
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Ion channels: a first view of K⁺ channels in atomic glory
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