Biobank-scale inference of ancestral recombination graphs enables genealogical analysis of complex traits

Genome-wide genealogies compactly represent the evolutionary history of a set of genomes and inferring them from genetic data has the potential to facilitate a wide range of analyses. We introduce a method, ARG-Needle, for accurately inferring biobank-scale genealogies from sequencing or genotyping...

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Bibliographic Details
Main Authors: Zhang, BC, Biddanda, A, Gunnarsson, ÁF, Cooper, F, Palamara, P
Format: Journal article
Language:English
Published: Springer Nature 2023