Ileal pouch dialysate is cytotoxic to epithelial cell lines, but not to CaCo-2 monolayers.

OBJECTIVE: All patients with ileal pouch-anal anastomosis (IPAA) have some degree of villous atrophy, mucin changes and chronic inflammation. The mechanism underlying these changes is unknown. This study investigates the hypothesis that luminal factor(s) may affect epithelial cells in in-vitro studi...

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Bibliographic Details
Main Authors: Merrett, M, Owen, R, Jewell, D
Format: Journal article
Language:English
Published: 1997