BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals.

The interpretation of genome sequences requires reliable and standardized methods to assess protein function at high throughput. Here we describe a fast and reliable pipeline to study protein function in mammalian cells based on protein tagging in bacterial artificial chromosomes (BACs). The large s...

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Bibliographic Details
Main Authors: Poser, I, Sarov, M, Hutchins, JR, Hériché, J, Toyoda, Y, Pozniakovsky, A, Weigl, D, Nitzsche, A, Hegemann, B, Bird, A, Pelletier, L, Kittler, R, Hua, S, Naumann, R, Augsburg, M, Sykora, M, Hofemeister, H, Zhang, Y, Nasmyth, K, White, K, Dietzel, S, Mechtler, K, Durbin, R, Stewart, A, Peters, J
Format: Journal article
Language:English
Published: 2008