Techniques for the detection of autophagy in primary mammalian cells

Autophagy is a lysosomal catabolic pathway responsible for the degradation of cytoplasmic constituents. Autophagy is primarily a survival pathway for recycling cellular material in times of nutrient starvation, and in response to hypoxia, endoplasmic reticulum stress, and other stresses, regulated t...

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Bibliographic Details
Main Authors: Puleston, D, Phadwal, K, Watson, A, Soilleux, E, Chittaranjan, S, Bortnik, S, Gorski, S, Ktistakis, N, Simon, A
Format: Journal article
Language:English
Published: Cold Spring Harbor Laboratory Press 2015