The solution and crystal structures of a module pair from the Staphylococcus aureus-binding site of human fibronectin--a tale with a twist.

An important goal of structural studies of modular proteins is to determine the inter-module orientation, which often influences biological function. The N-terminal domain of human fibronectin (Fn) is composed of a string of five type 1 modules (F1). Despite their small size, to date F1 modules have...

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Bibliographic Details
Main Authors: Rudiño-Piñera, E, Ravelli, R, Sheldrick, G, Nanao, M, Korostelev, V, Werner, J, Schwarz-Linek, U, Potts, JR, Garman, E
Format: Journal article
Language:English
Published: 2007