Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon.

CD8+ T cell responses can be generated against antigens that are not expressed directly within antigen-presenting cells (APCs), through a process known as cross-priming. To initiate cross-priming, APCs must both capture extracellular antigen and receive specific activation signals. We have investiga...

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Bibliographic Details
Main Authors: Le Bon, A, Etchart, N, Rossmann, C, Ashton, M, Hou, S, Gewert, D, Borrow, P, Tough, D
Format: Journal article
Language:English
Published: 2003