An alternative conformation of the T-cell receptor alpha constant region.
Alphabeta T-cell receptors (TcRs) play a central role in cellular immune response. They are members of the Ig superfamily, with extracellular regions of the alpha and beta chains each comprising a V-type domain and a C-type domain. We have determined the ectodomain structure of an alphabeta TcR, whi...
主要な著者: | van Boxel, G, Holmes, S, Fugger, L, Jones, E |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
2010
|
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