Human mesenchymal tumour-associated macrophages differentiate into osteoclastic bone-resorbing cells.

The cellular mechanisms which account for the formation of osteoclasts and bone resorption associated with enlarging benign and malignant mesenchymal tumours of bone are uncertain. Osteoclasts are marrow-derived, multinucleated, bone-resorbing cells which express a macrophage phenotype. We have dete...

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Bibliographic Details
Main Authors: Yang, T, Sabokbar, A, Gibbons, C, Athanasou, N
Format: Journal article
Language:English
Published: 2002