The interactions of APC, E-cadherin and beta-catenin in tumour development and progression.
Much progress has been made in identifying genes mutated during the development of colorectal carcinoma. Mutation of the APC gene in particular appears to be fundamental for colorectal tumour initiation. In contrast, loss of expression of E-cadherin appears to be a late event, which may be important...
| Main Authors: | , |
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| Format: | Journal article |
| Sprog: | English |
| Udgivet: |
1997
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