Drug oxidation by Cytochrome P450BM3: metabolite synthesis and discovering new P450 reaction types
There is intense interest in late‐stage catalytic CH bond functionalization as an integral part of synthesis. Effective catalysts must have a broad substrate range and tolerate diverse functional groups. Drug molecules provide a good test of these attributes of a catalyst. A library of P450BM3 muta...
| Główni autorzy: | , , , , , |
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| Format: | Journal article |
| Język: | English |
| Wydane: |
Wiley
2015
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