The structural basis of specific base-excision repair by uracil-DNA glycosylase.

The 1.75-A crystal structure of the uracil-DNA glycosylase from herpes simplex virus type-1 reveals a new fold, distantly related to dinucleotide-binding proteins. Complexes with a trideoxynucleotide, and with uracil, define the DNA-binding site and allow a detailed understanding of the exquisitely...

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Hlavní autoři: Savva, R, McAuley-Hecht, K, Brown, T, Pearl, L
Médium: Journal article
Jazyk:English
Vydáno: 1995