TNFα in the regulation of Treg and Th17 cells in rheumatoid arthritis and other autoimmune inflammatory diseases

TNFα is a principal pro-inflammatory cytokine vital for immunity to infections. However, its excessive production is involved in chronic inflammation and disease pathology in autoimmune diseases. Evidence for its pathogenic role is validated by the fact that its neutralisation by therapeutic agents...

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Bibliographic Details
Main Authors: Bystrom, J, Clancy, F, Taher, T, Mangat, P, Jawad, A, Williams, R, Mageed, R
Format: Journal article
Language:English
Published: Elsevier 2016