Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies

Clinical and neuropathological similarities between dementia with Lewy bodies (DLB), Parkinson's and Alzheimer's diseases (PD and AD, respectively) suggest that these disorders may share etiology. To test this hypothesis, we have performed an association study of 54 genomic regions, previo...

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Main Authors:	Bras, J, Guerreiro, R, Darwent, L, Parkkinen, L, Ansorge, O, Escott-Price, V, Hernandez, DG, Nalls, MA, Clark, LN, Honig, LS, Marder, K, Van Der Flier, WM, Lemstra, A, Scheltens, P, Rogaeva, E, St George-Hyslop, P, Londos, E, Zetterberg, H, Ortega-Cubero, S, Pastor, P, Ferman, TJ, Graff-Radford, NR, Ross, OA, Barber, I, Braae, A, Brown, K, Morgan, K, Maetzler, W, Berg, D, Troakes, C, Al-Sarraj, S, Lashley, T, Compta, Y, Revesz, T, Lees, A, Cairns, N, Halliday, GM, Mann, D, Pickering-Brown, S, Dickson, DW, Singleton, A, Hardy, J
格式:	Journal article
语言:	English
出版:	Oxford University Press 2014

Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies

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