Compensation for dystrophin-deficiency: ADAM12 overexpression in skeletal muscle results in increased alpha 7 integrin, utrophin and associated glycoproteins.

Compensation for dystrophin-deficiency: ADAM12 overexpression in skeletal muscle results in increased alpha 7 integrin, utrophin and associated glycoproteins.

Mouse models for genetic diseases are among the most powerful tools available for developing and testing new treatment strategies. ADAM12 is a disintegrin and metalloprotease, previously demonstrated to significantly alleviate the pathology of mdx mice, a model for Duchenne muscular dystrophy in hum...

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Bibliographische Detailangaben
Hauptverfasser:	Moghadaszadeh, B, Albrechtsen, R, Guo, LT, Zaik, M, Kawaguchi, N, Borup, R, Kronqvist, P, Schroder, H, Davies, K, Voit, T, Nielsen, F, Engvall, E, Wewer, U
Format:	Journal article
Sprache:	English
Veröffentlicht:	2003

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