Exchangeability of mammalian DNA ligases between base excision repair pathways.
In mammalian cells, DNA ligase IIIalpha and DNA ligase I participate in the short- and long-patch base excision repair pathways, respectively. Using an in vitro repair assay employing DNA ligase-depleted cell extracts and DNA substrates containing a single lesion repaired either through short-patch...
Главные авторы: | , , |
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Формат: | Journal article |
Язык: | English |
Опубликовано: |
2004
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