Exchangeability of mammalian DNA ligases between base excision repair pathways.

In mammalian cells, DNA ligase IIIalpha and DNA ligase I participate in the short- and long-patch base excision repair pathways, respectively. Using an in vitro repair assay employing DNA ligase-depleted cell extracts and DNA substrates containing a single lesion repaired either through short-patch...

Полное описание

Библиографические подробности
Главные авторы: Sleeth, K, Robson, R, Dianov, G
Формат: Journal article
Язык:English
Опубликовано: 2004