Effects of cell cycle variability on lineage and population measurements of messenger RNA abundance

Effects of cell cycle variability on lineage and population measurements of messenger RNA abundance

Many models of gene expression do not explicitly incorporate a cell cycle description. Here, we derive a theory describing how messenger RNA (mRNA) fluctuations for constitutive and bursty gene expression are influenced by stochasticity in the duration of the cell cycle and the timing of DNA replica...

Полное описание

Библиографические подробности
Главные авторы:	Perez-Carrasco, R, Beentjes, C, Grima, R
Формат:	Journal article
Язык:	English
Опубликовано:	Royal Society 2020

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