Tsc1-mTORC1 signaling controls striatal dopamine release and cognitive flexibility

Tuberous Sclerosis Complex (TSC) is a neurodevelopmental disorder caused by mutations in TSC1 or TSC2, which encode proteins that negatively regulate mTOR complex 1 (mTORC1). TSC is associated with significant cognitive, psychiatric, and behavioral problems, collectively termed TSC-Associated Neurop...

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Bibliographic Details
Main Authors: Kosillo, P, Doig, NM, Ahmed, KM, Agopyan-Miu, AHCW, Wong, CD, Conyers, L, Threlfell, S, Magill, PJ, Bateup, HS
Format: Journal article
Language:English
Published: Nature Research 2019