Synthesis of the bicyclic dienone core of the antitumor agent ottelione B.

The intramolecular Diels-Alder adduct 12 was converted via dimesylate 20 into dienone 7, which represents the unusual, and apparently quite stable, core of the antitumor agent ottelione B (1).

Bibliographic Details
Main Authors: Clive, D, Fletcher, S
Format: Journal article
Language:English
Published: 2002