The role of Adaptor Protein 3 in cytotoxic T lymphocytes
Cytotoxic T lymphocytes (CTL) kill virally infected and tumourigenic cells via the regulated secretion of specialised secretory lysosomes. These secretory lysosomes contain cytolytic effector molecules, such as perforin and granzymes, which are able to induce apoptosis in target cells. Secretion occ...
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Format: | Thesis |
Language: | English |
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2009
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