Evaluating beta-amino acids as enantioselective organocatalysts of the Hajos-Parrish-Eder-Sauer-Wiechert reaction.

A systematic study of the effect of substitution within the beta-amino acid framework indicates that both beta(2)- and beta(3)-amino acids catalyse the Hajos-Parrish-Eder-Sauer-Wiechert reaction with poor to reasonable levels of enantioselectivity. These results led to the evaluation of the conforma...

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Bibliographic Details
Main Authors: Davies, S, Russell, A, Sheppard, R, Smith, A, Thomson, J
Format: Journal article
Language:English
Published: 2007