Characterisation of novel phosphorylation sites on FANCD2 and their role in the Fanconi anaemia pathway
<p>Interstrand crosslinks (ICLs) are a highly deleterious form of DNA damage because they link the two strands of DNA, blocking replication, transcription and chromosome segregation. At the center of ICL repair is the FANCD2/FANCI complex, recruitment of which onto the ICL is a critical step f...
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| Format: | Thesis |
| Language: | English |
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2018
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