Unexpected structure for the N-terminal domain of hepatitis C virus envelope glycoprotein E1

Hepatitis C virus (HCV) infection remains a major health problem worldwide. HCV entry into host cells and membrane fusion are achieved by two envelope glycoproteins, E1 and E2. We report here the 3.5-Å resolution crystal structure of the N-terminal domain of the HCV E1 ectodomain, which reveals a co...

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Bibliographic Details
Main Authors: El Omari, K, Iourin, O, Kadlec, J, Sutton, G, Harlos, K, Grimes, J, Stuart, D
Format: Journal article
Language:English
Published: Springer Nature 2014