Interleukin-1 directly stimulates the release of corticotrophin releasing factor from rat hypothalamus.
While interleukin-1 (IL-1), a monocyte-derived polypeptide, clearly stimulates the hypothalamo-pituitary-adrenal (HPA) axis, its precise site of action is controversial. In these studies, the possibility of a hypothalamic and/or a pituitary site of action was investigated in vitro, using incubated r...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1989
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