Tertiary element interaction in HIV-1 TAR
HIV-1 replication requires binding to occur between Trans-activation Response Element (TAR) RNA and the TAT protein. This TAR-TAT binding depends on the conformation of TAR, and therapeutic development has attempted to exploit this dynamic behavior. Here we simulate TAR dynamics in the context of mu...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
American Chemical Society
2016
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