Wild-type, but not mutant N296H, human tau restores Aβ-mediated inhibition of LTP in tau(-/-) mice
Microtubule associated protein tau (MAPT) is involved in the pathogenesis of Alzheimer's disease and many forms of frontotemporal dementia (FTD). We recently reported that Aβ-mediated inhibition of hippocampal long-term potentiation (LTP) in mice requires tau. Here, we asked whether expression...
Main Authors: | , , , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Frontiers Media
2017
|