Wild-type, but not mutant N296H, human tau restores Aβ-mediated inhibition of LTP in tau(-/-) mice

Microtubule associated protein tau (MAPT) is involved in the pathogenesis of Alzheimer's disease and many forms of frontotemporal dementia (FTD). We recently reported that Aβ-mediated inhibition of hippocampal long-term potentiation (LTP) in mice requires tau. Here, we asked whether expression...

Full description

Bibliographic Details
Main Authors: Vargas-Caballero, M, Denk, F, Wobst, H, Arch, E, Pegasiou, C, Oliver, P, Shipton, O, Paulsen, O, Wade-Martins, R
Format: Journal article
Language:English
Published: Frontiers Media 2017