Improved HIV-1 specific T-cell responses by short-interval DNA tattooing as compared to intramuscular immunization in non-human primates.

The new intradermal DNA delivery technique, termed DNA tattooing might overcome the discrepancy between the encouraging immunogenicity results obtained with DNA vaccines in murine studies and the poor results obtained in non-human primates and humans, the so called "simian barrier". Here,...

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Bibliographic Details
Main Authors: Verstrepen, B, Bins, A, Rollier, C, Mooij, P, Koopman, G, Sheppard, N, Sattentau, Q, Wagner, R, Wolf, H, Schumacher, T, Heeney, J, Haanen, J
Format: Journal article
Language:English
Published: 2008