Reconstruction of complexes of histone and superhelical nuclear DNA.
When HeLa cells are lysed in solutions containing a non-ionic detergent and 2 M-NaCl, structures are released that retain many of the morphological features of nuclei. These nucleoids contain all the nuclear RNA and DNA but few of the proteins characteristic of chromatin. Their DNA is supercoiled an...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1981
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