Haplotype-specific linkage disequilibrium patterns define the genetic topography of the human MHC.

Detailed knowledge of linkage disequilibrium (LD) is regarded as a prerequisite for population-based disease gene mapping. Variable patterns across the human genome are now recognized, both between regions and populations. Here, we demonstrate that LD may also vary within a genomic region in a haplo...

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Bibliographic Details
Main Authors: Ahmad, T, Neville, M, Marshall, SE, Armuzzi, A, Mulcahy-Hawes, K, Crawshaw, J, Sato, H, Ling, K, Barnardo, M, Goldthorpe, S, Walton, R, Bunce, M, Jewell, D, Welsh, K
Format: Journal article
Language:English
Published: 2003