Normothermic machine perfused organs as models of drug pharmacokinetics and therapeutic delivery
<p>Less than 10% of drug candidates successfully pass through clinical trials and gain regulatory approval. One of the causes of translational failure is poor drug pharmacokinetics which are inadequately predicted by preclinical studies. Despite improvements in pharmacokinetic prediction in re...
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| Format: | Thesis |
| Language: | English |
| Published: |
2022
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