Development of an algorithm to discriminate between plasmid- and chromosomal-mediated AmpC β-lactamase production in Escherichia coli by elaborate phenotypic and genotypic characterization

Objectives AmpC-β-lactamase production is an under-recognized antibiotic resistance mechanism that renders Gram-negative bacteria resistant to common β-lactam antibiotics, similar to the well-known ESBLs. For infection control purposes, it is important to be able to discriminate between plasmid-medi...

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Bibliographic Details
Main Authors: Coolen, JPM, den Drijver, EPM, Kluytmans, JAJW, Verweij, JJ, Lamberts, BA, Soer, JACJ, Verhulst, C, Wertheim, HFL, Kolwijck, E
Format: Journal article
Language:English
Published: Oxford University Press 2019