The haptoglobin 2-2 genotype is associated with a reduced incidence of Plasmodium falciparum malaria in children on the coast of Kenya

Background: Haptoglobin (Hp) genotype determines the efficiency of haemoglobin clearance after malaria-induced hemolysis and alters antioxidant and immune functions. The Hp² allele is thought to have spread under strong selection pressure, but it is unclear whether this is due to protection from mal...

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Bibliographic Details
Main Authors: Atkinson, S, Mwangi, T, Uyoga, S, Ogada, E, Marsh, K, Prentice, A, Williams, T
Other Authors: Infectious Diseases Society of America
Format: Journal article
Language:English
Published: University of Chicago Press 2007
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