The haptoglobin 2-2 genotype is associated with a reduced incidence of Plasmodium falciparum malaria in children on the coast of Kenya
Background: Haptoglobin (Hp) genotype determines the efficiency of haemoglobin clearance after malaria-induced hemolysis and alters antioxidant and immune functions. The Hp² allele is thought to have spread under strong selection pressure, but it is unclear whether this is due to protection from mal...
Main Authors: | , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
University of Chicago Press
2007
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