Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

The eukaryotic initiation factor 3 (eIF3) plays an important role in translation initiation, acting as a docking site for several eIFs that assemble on the 40S ribosomal subunit. Here, we use mass spectrometry to probe the subunit interactions within the human eIF3 complex. Our results show that the...

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Bibliografische gegevens
Hoofdauteurs: Zhou, M, Sandercock, A, Fraser, C, Ridlova, G, Stephens, E, Schenauer, MR, Yokoi-Fong, T, Barsky, D, Leary, J, Hershey, J, Doudna, J, Robinson, C
Formaat: Journal article
Taal:English
Gepubliceerd in: 2008