Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

The eukaryotic initiation factor 3 (eIF3) plays an important role in translation initiation, acting as a docking site for several eIFs that assemble on the 40S ribosomal subunit. Here, we use mass spectrometry to probe the subunit interactions within the human eIF3 complex. Our results show that the...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Zhou, M, Sandercock, A, Fraser, C, Ridlova, G, Stephens, E, Schenauer, MR, Yokoi-Fong, T, Barsky, D, Leary, J, Hershey, J, Doudna, J, Robinson, C
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2008

समान संसाधन

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प्रकाशित: (2007)

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द्वारा: Leary, J, और अन्य
प्रकाशित: (2009)

Unified nomenclature for the subunits of eukaryotic initiation factor 3.
द्वारा: Browning, K, और अन्य
प्रकाशित: (2001)

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द्वारा: Ghosh, S, और अन्य
प्रकाशित: (2015)

Analysis of a role of hypusinated eukaryotic initiation factor 5A (EIF5A) and its isoform EIF5A2 in embryonic stem cell self-renewal and differentiation.
द्वारा: Lee, Su Qi.
प्रकाशित: (2013)

Mass spectrometry of ribosomes and ribosomal subunits.
द्वारा: Benjamin, DR, और अन्य
प्रकाशित: (1998)

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द्वारा: Wortham, N, और अन्य
प्रकाशित: (2014)

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A fission yeast homolog of Int-6, the mammalian oncoprotein and eIF3 subunit, induces drug resistance when overexpressed.
द्वारा: Crane, R, और अन्य
प्रकाशित: (2000)

Modular architecture of eukaryotic RNase P and RNase MRP revealed by electron microscopy
द्वारा: Hipp, Katharina, और अन्य
प्रकाशित: (2012)

Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions.
द्वारा: Barrera, N, और अन्य
प्रकाशित: (2009)

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द्वारा: Flavin, R, और अन्य
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Polyamines control eIF5A hypusination, TFEB translation, and autophagy to reverse B cell senescence
द्वारा: Zhang, H, और अन्य
प्रकाशित: (2019)

The archaeal origins of the eukaryotic translational system
द्वारा: Hartman, Hyman, और अन्य
प्रकाशित: (2015)

NMR study of eukaryotic translation termination
द्वारा: Wong, Leo E
प्रकाशित: (2013)

Subunit exchange of polydisperse proteins: mass spectrometry reveals consequences of alphaA-crystallin truncation.
द्वारा: Aquilina, J, और अन्य
प्रकाशित: (2005)

Elucidating the role of eIF6 in the endothelial response to shear stress
द्वारा: Simpson, L
प्रकाशित: (2020)

Subunit exchange of polydisperse proteins: mass spectrometry reveals consequences of alphaA-crystallin truncation
द्वारा: Aquilina, J, और अन्य
प्रकाशित: (2005)

The human eukaryotic initiation factor 4AI gene (EIF4A1) contains multiple regulatory elements that direct high-level reporter gene expression in mammalian cell lines.
द्वारा: Quinn, C, और अन्य
प्रकाशित: (1999)

Subunit architecture of intact protein complexes from mass spectrometry and homology modeling.
द्वारा: Taverner, T, और अन्य
प्रकाशित: (2008)

Subunit exchange of multimeric protein complexes. Real-time monitoring of subunit exchange between small heat shock proteins by using electrospray mass spectrometry.
द्वारा: Sobott, F, और अन्य
प्रकाशित: (2002)

Subunit exchange of multimeric protein complexes. Real-time monitoring of subunit exchange between small heat shock proteins by using electrospray mass spectrometry
द्वारा: Sobott, F, और अन्य
प्रकाशित: (2002)

Protein subunit interactions and structural integrity of amyloidogenic transthyretins: evidence from electrospray mass spectrometry.
द्वारा: Nettleton, E, और अन्य
प्रकाशित: (1998)

An oncogenic role of eIF3e/INT6 in human breast cancer.
द्वारा: Grzmil, M, और अन्य
प्रकाशित: (2010)

Eukaryotic promoters?
द्वारा: Proudfoot, N
प्रकाशित: (1979)

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द्वारा: van Duijn, E, और अन्य
प्रकाशित: (2012)

Structural and dynamic features of the eukaryotic translation initiation pathway
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