Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

The eukaryotic initiation factor 3 (eIF3) plays an important role in translation initiation, acting as a docking site for several eIFs that assemble on the 40S ribosomal subunit. Here, we use mass spectrometry to probe the subunit interactions within the human eIF3 complex. Our results show that the...

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Bibliographic Details
Main Authors:	Zhou, M, Sandercock, A, Fraser, C, Ridlova, G, Stephens, E, Schenauer, MR, Yokoi-Fong, T, Barsky, D, Leary, J, Hershey, J, Doudna, J, Robinson, C
Format:	Journal article
Language:	English
Published:	2008

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