Identification of ischemia-regulated phosphorylation sites in connexin43: A possible target for the antiarrhythmic peptide analogue rotigaptide (ZP123).

Previous studies suggest that dephosphorylation of connexin43 (Cx43) is related to uncoupling of gap junction communication, which plays an important role in the genesis of ischemia-induced ventricular tachycardia. We studied changes in Cx43 phosphorylation during global ischemia in the absence and...

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Bibliographic Details
Main Authors: Axelsen, L, Stahlhut, M, Mohammed, S, Larsen, B, Nielsen, MS, Holstein-Rathlou, N, Andersen, S, Jensen, O, Hennan, J, Kjølbye, A
Format: Journal article
Language:English
Published: 2006