Lamivudine treatment can overcome cytotoxic T-cell hyporesponsiveness in chronic hepatitis B: new perspectives for immune therapy.

The hepatitis B virus (HBV) cytotoxic T lymphocyte (CTL) response in patients with chronic HBV infection is generally weak or totally undetectable. This inability to mount protective CTL responses is believed to be a crucial determinant of viral persistence, and its correction represents an importan...

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Bibliographic Details
Main Authors: Boni, C, Penna, A, Ogg, G, Bertoletti, A, Pilli, M, Cavallo, C, Cavalli, A, Urbani, S, Boehme, R, Panebianco, R, Fiaccadori, F, Ferrari, C
Format: Journal article
Language:English
Published: 2001