Conformational plasticity of the ULK3 kinase domain

The human protein kinase ULK3 regulates the timing of membrane abscission, thus being involved in exosome budding and cytokinesis. Herein, we present the first high-resolution structures of the ULK3 kinase domain. Its unique features are explored against the background of other ULK kinases. An inhib...

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Autori principali: Mathea, S, Salah, E, Tallant, C, Chatterjee, D, Berger, B-T, Konietzny, R, Müller-Knapp, S, Kessler, BM, Knapp, S
Natura: Journal article
Lingua:English
Pubblicazione: Portland Press 2021