Conformational plasticity of the ULK3 kinase domain
The human protein kinase ULK3 regulates the timing of membrane abscission, thus being involved in exosome budding and cytokinesis. Herein, we present the first high-resolution structures of the ULK3 kinase domain. Its unique features are explored against the background of other ULK kinases. An inhib...
Main Authors: | Mathea, S, Salah, E, Tallant, C, Chatterjee, D, Berger, B-T, Konietzny, R, Müller-Knapp, S, Kessler, BM, Knapp, S |
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Format: | Journal article |
Language: | English |
Published: |
Portland Press
2021
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