Modulation of microenvironment signals by proteolytic shedding of cell surface ECM receptors

Multicellular organisms are composed of cells and extracellular matrix (ECM). ECM is a network of multidomain macromolecules that fills gaps between cells. It acts as a glue to connect cells, provides scaffolding for migrating cells, and pools cytokines and growth factors. ECM also directly sends si...

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Bibliographic Details
Main Author: Itoh, Y
Format: Journal article
Language:English
Published: Frontiers Media 2021