Combined vaccination against IL-5 and eotaxin blocks eosinophilia in mice.

Interleukin-5 (IL-5) is a cytokine which is essential for the maturation of eosinophils in bone marrow and for their release into the blood. Eotaxin is a CC type chemokine implicated in the recruitment of eosinophils in a variety of inflammatory disorders. Since eosinophil-activity is governed by th...

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Bibliographic Details
Main Authors: Zou, Y, Sonderegger, I, Lipowsky, G, Jennings, G, Schmitz, N, Landi, M, Kopf, M, Bachmann, M
Format: Journal article
Language:English
Published: 2010