The effect of topology on the structure and free energy landscape of DNA kissing complexes.
We use a recently developed coarse-grained model for DNA to study kissing complexes formed by hybridization of complementary hairpin loops. The binding of the loops is topologically constrained because their linking number must remain constant. By studying systems with linking numbers -1, 0, or 1 we...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
American Institute of Physics
2012
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